Prescription Nsaids Aerosol Medication Diclofenac Sodium Spray For Osteoarthritis

Prescription Nsaids Aerosol Medication Diclofenac Sodium Spray For Osteoarthritis

Product : Diclofenac Sodium Spray

Specification : 0.5mg/dose, 160doses/bottle, 400doses/bottle

Standard : BP, USP

Packing : one bottle/box

Indications :

Diclofenac Sodium Spray contains the active substance diclofenac sodium, which belongs to the group of non-steroidal antiinflammatory drugs (NSAID). Diclofenac Sodium Spray Gel is used to relieve the acute pain and swelling affecting small or medium-sized joints and surrounding tissues.

Pharmacodynamics

Diclofenac is an acetic acid nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Diclofenac is used to treat pain, dysmenorrhea, ocular inflammation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and actinic keratosis

Mechanism of action

The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation.